Lungs and Asthma

Lungs and Asthma

Zhang, G., et al., The Anti-inflammatory Effect of Hydrogen on Lung Transplantation Model of Pulmonary Microvascular Endothelial Cells During Cold Storage Period. Transplantation, 2018. 102(8): p. 1253-1261.

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Wu, D., et al., Hydrogen protects against hyperoxia-induced apoptosis in type II alveolar epithelial cells via activation of PI3K/Akt/Foxo3a signaling pathway. Biochem Biophys Res Commun, 2018. 495(2): p. 1620-1627.

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Lu, W., et al., Hydrogen gas inhalation protects against cigarette smoke-induced COPD development in mice. J Thorac Dis, 2018. 10(6): p. 3232-3243.

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Haam, S., et al., Hydrogen gas inhalation during ex vivo lung perfusion of donor lungs recovered after cardiac death. J Heart Lung Transplant, 2018.

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Chen, M., et al., Hydrogen protects lung from hypoxia/re-oxygenation injury by reducing hydroxyl radical production and inhibiting inflammatory responses. Sci Rep, 2018. 8(1): p. 8004.

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Zhao, C., et al., Changes in IL-4 and IL-13 expression in allergic-rhinitis treated with hydrogen-rich saline in guinea-pig model. Allergol Immunopathol (Madr), 2017.

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Yu, S., et al., Hydrogen-rich saline attenuates eosinophil activation in a guinea pig model of allergic rhinitis via reducing oxidative stress. J Inflamm (Lond), 2017. 14: p. 1.

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Ying, Y., et al., Protective effect of hydrogen-saturated saline on acute lung injury induced by oleic acid in rats. J Orthop Surg Res, 2017. 12(1): p. 134.

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Yan, W.M., et al., Effects of hydrogen-rich saline on endotoxin-induced uveitis. Med Gas Res, 2017. 7(1): p. 9-18.

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Xiao, L. and N. Miwa, Hydrogen-rich water achieves cytoprotection from oxidative stress injury in human gingival fibroblasts in culture or 3D-tissue equivalents, and wound-healing promotion, together with ROS-scavenging and relief from glutathione diminishment. Hum Cell, 2017. 30(2): p. 72-87.

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Wang, K., et al., Hydrogen-rich saline prevents the down regulation of claudin-5 protein in septic rat lung via the PI3K/Akt signaling pathway. Int J Clin Exp Med, 2017. 10(8): p. 11717-11727.

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Takahashi, M., et al., Immersing lungs in hydrogen-rich saline attenuates lung ischaemia-reperfusion injury. Eur J Cardiothorac Surg, 2017. 51(3): p. 442-448.

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Suzuki, Y., et al., Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice. Biochem Biophys Res Commun, 2017. 492(1): p. 74-81.

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Liu, Z., et al., Effect of Hydrogen-Rich Saline on Postoperative Intra-Abdominal Adhesion Bands Formation in Mice. Med Sci Monit, 2017. 23: p. 5363-5373.

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Liu, X., et al., Hydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model. Int J Chron Obstruct Pulmon Dis, 2017. 12: p. 1309-1324.

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Li, Q., Y. Tanaka, and N. Miwa, Influence of hydrogen-occluding-silica on migration and apoptosis in human esophageal cells in vitro. Med Gas Res, 2017. 7(2): p. 76-85.

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Kim, J., H.J. Lee, and S.H. Hong, Inhibition of streptococcal biofilm by hydrogen water. J Dent, 2017. 58: p. 34-39.

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He, Y., et al., Effects of Hydrogen Gas Inhalation on Endometriosis in Rats. Reprod Sci, 2017. 24(2): p. 324-331.

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Ge, L., et al., Hydrogen-rich saline attenuates spinal cord hemisection-induced testicular injury in rats.Oncotarget, 2017. 8(26): p. 42314-42331.

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Dong, W.W., et al., Protective Effects of Hydrogen-Rich Saline Against Lipopolysaccharide-Induced Alveolar Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis. Med Sci Monit, 2017. 23: p. 2357-2364.

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Ushida, T., et al., Molecular hydrogen ameliorates several characteristics of preeclampsia in the Reduced Uterine Perfusion Pressure (RUPP) rat model. Free Radic Biol Med, 2016. 101: p. 524-533.

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Tao, B., et al., Effects of hydrogen-rich saline on aquaporin 1, 5 in septic rat lungs. J Surg Res, 2016. 202(2): p. 291-8.

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Muramatsu, Y., et al., Hydrogen-rich water ameliorates bronchopulmonary dysplasia (BPD) in newborn rats. Pediatr Pulmonol, 2016. 51(9): p. 928-35.

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Miyazaki, N., et al., Preventive Effect of Hydrogen Water on the Development of Detrusor Overactivity in a Rat Model of Bladder Outlet Obstruction. J Urol, 2016. 195(3): p. 780-7.

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Meng, C., et al., Protection of donor lung inflation in the setting of cold ischemia against ischemia-reperfusion injury with carbon monoxide, hydrogen, or both in rats. Life Sci, 2016. 151: p. 199-206.

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Huang, S.L., J. Jiao, and H.W. Yan, Hydrogen-rich saline attenuates steroid-associated femoral head necrosis through inhibition of oxidative stress in a rabbit model. Exp Ther Med, 2016. 11(1): p. 177-182.

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Hong, Y., et al., Combination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model. Exp Ther Med, 2016. 11(6): p. 2590-2596.

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He, X., et al., Hydrogen-rich Water Exerting a Protective Effect on Ovarian Reserve Function in a Mouse Model of Immune Premature Ovarian Failure Induced by Zona Pellucida Chin Med J (Engl), 2016. 129(19): p. 2331-7.

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Hara, F., et al., Molecular Hydrogen Alleviates Cellular Senescence in Endothelial Cells. Circ J, 2016.

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Diao, M., et al., Hydrogen Gas Inhalation Attenuates Seawater Instillation-Induced Acute Lung Injury via the Nrf2 Pathway in Rabbits. Inflammation, 2016.

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Chen, S., W. Jiang, and X.H. Wang, Protective Effect of Hydrogen Injected Subcutaneously on Testicular Tissues of Rats Exposed to Cigarette Smoke. West Indian Med J, 2016.

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Chen, L., et al., Re: Preventive Effect of Hydrogen Water on the Development of Detrusor Overactivity in a Rat Model of Bladder Outlet Obstruction: N. Miyazaki, O. Yamaguchi, M. Nomiya, K. Aikawa and J. Kimura J Urol 2016;195:780-787. J Urol, 2016. 196(2): p. 620-1.

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Zhang, Y., Y. Liu, and J. Zhang, Saturated hydrogen saline attenuates endotoxin-induced lung dysfunction. J Surg Res, 2015. 198(1): p. 41-9.

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Zhai, Y., et al., Hydrogen-rich saline ameliorates lung injury associated with cecal ligation and puncture-induced sepsis in rats. Exp Mol Pathol, 2015. 98(2): p. 268-276.

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Yuan, L., et al., Administration of hydrogen-rich saline in mice with allogeneic hematopoietic stem-cell transplantation. Med Sci Monit, 2015. 21: p. 749-54.

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Wu, Q., et al., Hydrogen water alleviates lung injury induced by one-lung ventilation. J Surg Res, 2015.

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Sato, C., et al., Effects of hydrogen water on paraquat-induced pulmonary fibrosis in mice. The Kitasato medical journal 2015. 45(1): p. 9-16.

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Nakata, K., et al., Stimulation of human damaged sperm motility with hydrogen molecule. Med Gas Res, 2015. 5(1): p. 2.

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Liu, R., et al., Lung inflation with hydrogen during the cold ischemia phase decreases lung graft injury in rats. Exp Biol Med (Maywood), 2015.

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Liu, H., et al., Combination therapy with nitric oxide and molecular hydrogen in a murine model of acute lung injury. Shock, 2015. 43(5): p. 504-11.

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Kishimoto, Y., et al., Hydrogen ameliorates pulmonary hypertension in rats by anti-inflammatory and antioxidant effects. J Thorac Cardiovasc Surg, 2015. 150(3): p. 645-654 e3.

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Hattori, Y., et al., Maternal molecular hydrogen treatment attenuates lipopolysaccharide-induced rat fetal lung injury. Free Radic Res, 2015. 49(8): p. 1026-37.

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Haam, S., et al., The effects of hydrogen gas inhalation during ex vivo lung perfusion on donor lungs obtained after cardiac death. Eur J Cardiothorac Surg, 2015. 48(4): p. 542-7.

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Guan, Z., et al., Effects of vitamin C, vitamin E, and molecular hydrogen on the placental function in trophoblast cells. Arch Gynecol Obstet, 2015.

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Chen, X., et al., Protective Effects of Hydrogen-Rich Saline on Rats with Smoke Inhalation Injury. Oxid Med Cell Longev, 2015. 2015: p. 106836.

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Chen, S. and W. Jiang, Effect of hydrogen injected subcutaneously on testicular tissues of rats exposed to cigarette smoke. Int J Clin Exp Med, 2015. 8(4): p. 5565-70.

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Zhang, J., et al., Effect of hydrogen-rich water on acute peritonitis of rat models. Int Immunopharmacol, 2014. 21(1): p. 94-101.

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Tomofuji, T., et al., Effects of hydrogen-rich water on aging periodontal tissues in rats. Sci Rep, 2014. 4: p. 5534.

Noda, K., et al., Hydrogen Preconditioning During Ex Vivo Lung Perfusion Improves the Quality of Lung Grafts in Rats. Transplantation 2014.

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Li, S., et al., Long-term treatment of hydrogen-rich saline abates testicular oxidative stress induced by nicotine in mice. J Assist Reprod Genet, 2014. 31(1): p. 109-14.

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Du, Z., et al., Protective effects of hydrogen-rich saline in uncontrolled hemorrhagic shock. Journal of Surgical Research, 2014. In press.

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Xiao, M., et al., Hydrogen-rich saline reduces airway remodeling via inactivation of NF-kappaB in a murine model of asthma. Eur Rev Med Pharmacol Sci, 2013. 17(8): p. 1033-43.

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Ning, Y., et al., Attenuation of cigarette smoke-induced airway mucus production by hydrogen-rich saline in rats. PLoS One, 2013. 8(12): p. e83429.

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Liu, W., et al., Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury.World J Gastroenterol, 2013. 19(4): p. 492-502.

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Kawamura, T., et al., Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo. Am J Physiol Lung Cell Mol Physiol, 2013. 304(10): p. L646-56.

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Xie, K., et al., Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis. Shock, 2012. 37(5): p. 548-55.

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Tanaka, Y., et al., Profiling molecular changes induced by hydrogen treatment of lung allografts prior to procurement. Biochem Biophys Res Commun, 2012. 425(4): p. 873-9.

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Shi, J., et al., Hydrogen saline is protective for acute lung ischaemia/reperfusion injuries in rats. Heart Lung Circ, 2012. 21(9): p. 556-63.

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Liang, C., et al., [Effect of hydrogen inhalation on p38 MAPK activation in rats with lipopolysaccharide- induced acute lung injury]. Nan Fang Yi Ke Da Xue Xue Bao, 2012. 32(8): p. 1211-3.

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Terasaki, Y., et al., Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress.American Journal of Physiology – Lung Cellular and Molecular Physiology, 2011. 301(4): p. L415-26.

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Sun, Q.A., et al., Hydrogen-Rich Saline Provides Protection Against Hyperoxic Lung Injury. Journal of Surgical Research, 2011. 165(1): p. E43-E49.

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Qiu, X., et al., Hydrogen inhalation ameliorates lipopolysaccharide-induced acute lung injury in mice. Int Immunopharmacol, 2011. 11(12): p. 2130-7.

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Liu, S.L., et al., Hydrogen Therapy may be a Novel and Effective Treatment for COPD. Front Pharmacol, 2011. 2: p. 19.

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Liu, S., et al., Consumption of hydrogen water reduces paraquat-induced acute lung injury in rats. Journal of Biomedicine & Biotechnology, 2011. 2011: p. 305086.

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Huang, C.S., et al., Hydrogen inhalation reduced epithelial apoptosis in ventilator-induced lung injury via a mechanism involving nuclear factor-kappa B activation. Biochemical and Biophysical Research Communications, 2011. 408(2): p. 253-8.

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Fang, Y., et al., Hydrogen-rich saline protects against acute lung injury induced by extensive burn in rat model.Journal of Burn Care and Research, 2011. 32(3): p. e82-91.

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Zheng, J., et al., Saturated hydrogen saline protects the lung against oxygen toxicity. Undersea & Hyperbaric Medicine, 2010. 37(3): p. 185-192.

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Qiu, X.C., et al., [Effect of hydrogen-rich saline on blood pressure and antioxidant ability of lung tissue in scalded rats following delayed resuscitation]. Zhonghua Shao Shang Za Zhi, 2010. 26(6): p. 435-8.

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Huang, C.S., et al., Hydrogen inhalation ameliorates ventilator-induced lung injury. Critical Care, 2010. 14(6): p. R234.

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Credit for this list given to the Molecular Hydrogen Institute.

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