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Molecular Hydrogen and Your Skin

By Adam Trainor August 23, 2019

As the industry leaders of Molecular Hydrogen supplements, we know a thing or two about the awesome benefits Molecular Hydrogen can do for your skin. Take a look at this post if you’d like to see how our products can help against:

○ Inflammatory skin conditions

○ Wounds and burns

○ Aging and wrinkles

Let's dive in!

Here at Vital Reaction® we’re well known for our industry leading Molecular Hydrogen Tablets and Hydrogen Inhalation Machines. While oral consumption of hydrogen water and inhalation are the most common methods of administration in the US, there is also a substantial body of research analyzing the efficacy of other methods, such as IV hydrogen and topical applications.

Based on the research, different methods of administration seem to work best for different conditions. Today we’re going to take a look at the uses and evidence for topical hydrogen. 

Generally this involves generating hydrogen water, and then applying it topically through a spray or bath. 

As you might expect, most of the research looking at topical hydrogen applications focuses primarily on its effects on your skin.

Broadly speaking, these can be broken down into a few categories:


  ○  Skin conditions (psoriasis, atopic dermatitis, etc)

  ○  Wound healing and burns

  ○  Aging and wrinkle formation


Let’s dive in!


Note- the FDA has not evaluated Vital Reaction® molecular hydrogen, and this is intended as educational content only. Vital Reaction® Molecular hydrogen is not intended to diagnose, treat or cure any disease.

Molecular Hydrogen and Inflammatory Skin Conditions

Several common skin conditions such as psoriasis, dermatitis, etc. fall under a broader category of chronic inflammatory diseases. There is some sort of persistent, pathological inflammation, and often an autoimmune component as well.

A major driver of inflammatory pathology is the over-production of reactive oxygen species (ROS). For a deep dive into inflammation and the role of ROS, take a look at our article on the role of oxidative stress in chronic pain and inflammation.

Long story short, chronic inflammation leads to the overproduction of free radicals, which cause more inflammation, which means more free radicals, and so on. It’s a vicious cycle. 

In the last decade, over 1400 research studies from across the globe have demonstrated that molecular hydrogen is a unique antioxidant with therapeutic potential for any disease process categorized by high levels of oxidative stress (translation: most chronic disease).


Psoriasis is a chronic inflammatory skin condition, which can also manifest as a nasty form of arthritis called psoriatic arthritis. It’s characterized by large, scaly plaques, which are often itchy and/or painful.

Unfortunately, it’s also really tough to treat. There’s no cure, and many of the pharmaceutical options for treating the symptoms come with some pretty nasty side effects. So if we could identify a natural therapy that helped to mitigate these symptoms with no side effects, it would be a game changer for these patients.

In a study published last year in the journal Scientific Reports, medical researchers in China explored whether or not topical hydrogen could make a difference for these types of diseases.

The study involved 74 subjects, half of whom were given topical hydrogen water; the other half was treated with regular water as a control. The subjects were treated with topical hydrogen twice a week for about 10-15 minutes per session. 

The hydrogen water had a hydrogen concentration of just 1 part per million (ppm) H2 gas. (For reference, our hydrogen tablets produce water with up to 10 ppm H2 gas).

After 8 weeks the hydrogen group saw substantial reductions in visible plaquing and symptoms compared to the control. A quarter of the hydrogen group saw up to 75% improvement in symptoms vs. just  2.9% in the control group. You can see some of their results in the images below:



Notably, these changes were observed after just 8 weeks. Equivalent results with common medications can take up to 12 weeks, with significant side effects. 

6 of the hydrogen patients were able to get off their drugs altogether. 

Interestingly, BMI also decreased in the patients receiving hydrogen therapy, though the researchers don’t know why...though this has also been seen in other H2 studies.

Wound Healing and Burns


Another area that’s received a fair amount of attention in the research community is the capacity for topical hydrogen to aid in wound and burn healing.

One animal model published in the journal Oxidative Medicine and Cellular Longevity (say that 5 times fast) looked at the effects of hydrogen water on oral wound healing in rats. This is a common approach to studying wounds, as we have a lot of standardized data for comparison. The researchers used hydrogen water with a concentration of about 5-7 ppm.

This is another one where pictures speak louder than words. 

In the picture below, the first image (a) represents the initial injury. The second image (b) is the control group that didn’t receive any hydrogen after one week. The third image (c) is the hydrogen treatment group after the same amount of time.




As the researchers noted, the differences in healing times between the two groups was substantial. 

The researchers also studied blood and cellular markers of inflammation and oxidative stress. Inflammatory chemicals and markers of oxidative stress were significantly lower in the hydrogen group compared to the control.

Scientists found that these extraordinary changes were brought about by hydrogen’s role as a selective NRF2 activator, and for hydrogen’s unique ability ability to decrease inflammatory cytokines and promote healing factors.

Hydrogen also appears to have potential for helping to repair burn damage. With any kind of serious burn, a critical aspect of care is getting treatment as quickly as possible. The longer the delay before treatment, the greater the risk of tissue death due to ischemic reperfusion injuries.

 Another rat study published in the journal Burns found that hydrogen was able to alleviate inflammation and speed wound healing, even in cases of burns that received delayed treatment, again due to activation of the NRF2 pathway.

This supports the findings from another study that showed that hydrogen prevented cellular apoptosis and reduced inflammation in severe burn models.

Finally, another pre-clinical trial published in the journal of Plastic, Reconstructive and Aesthetic Surgeons found that topical hydrogen prevented skin cell death during surgery involving large skin  incisions.

Granted these are all pre-clinical trials, and more research definitely needs to be done, but the results for hydrogen’s potential to affect wound and burn healing are very promising.

Skin Aging and Wrinkle Formation


And that brings us to everyone’s favorite topic: skin aging and wrinkles. We’ve previously discussed the role that molecular hydrogen can play in the overall aging process, but there are some really interesting studies looking specifically at skin.

Now let’s be realistic- aging is inevitable, and there is a certain genetic determinism to how your physical appearance may change with age. These factors are what experts refer to as intrinsic aging- genetic factors that you really can’t control.

However, there is also something known as extrinsic aging- this refers to environmental factors that may accelerate the aging process, like exposure to UV radiation from the sun.

Let’s look at UV radiation specifically.

One study from the journal Plos One looking at human subjects found that topical hydrogen mitigated UV induced redness and inflammation by over 20% compared to the control. They also found that the hydrogen treatment prevented DNA damage AND stimulated collagen production. 

They hypothesize that molecular hydrogen may prevent UV-induced skin inflammation and can modulate intrinsic skin aging and photoaging processes.” This confirmed the findings from a large number of animal studies.

Another small human trial found that 90 days of daily hydrogen baths significantly reduced wrinkles in 4 out of the 6 patients, and cellular analysis demonstrated similar UV-protective effects, AND once again promoted collagen formation.

In addition to UV damage from the sun, our skin is also aged via oxidative stress. Constantly exposed to a harsh external environment, skin cells experience some of the highest levels of oxidative stress in the body.

A study published in the journal Medical Gas Research found that topical hydrogen directly and substantially lowered markers of oxidative stress in skin cells, and prevented the formation of harmful chemical bonds that can accelerate the skin aging process. 

Another study looking at human subjects, published in the same journal, found that immersion in hydrogen water:


  ○  Improved peripheral blood flow (reactive oxygen species cause red blood cells to gum together, clogging capillaries) 

  ○  Improved skin moisture levels by 10% 

  ○  Cleansed keratin plugs in skin pores 2 -5x as much as normal water (via inhibition of lipid peroxidation)


Interestingly, the concentration of hydrogen in this study was extremely low, about 1/10th of that produced by Vital Reaction® molecular hydrogen tablets. 

Of course more research needs to be done, but molecular hydrogen is so safe and easy to use that if it even has just a fraction of the therapeutic potential suggested by the research, it will be a no-brainer to add to any daily skin regimen.


Curious to experience the benefits of hydrogen therapy for your skin?


At Vital Reaction® we sell a Dermal Hydrogen Therapy Device designed for use with our molecular hydrogen tablets. This dermal unit utilizes ultrasound to atomize the hydrogen rich water made with our tablets into tiny nano particles. This enables the free radical fighting power of hydrogen to diffuse deep into your skin, delivering targeted antioxidant therapy. 


Try it today risk free with our 30 day money back guarantee. Your skin will thank you!



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Why Use Molecular Hydrogen Tablets and Inhalation Machines?

In the body, H2 molecular hydrogen eliminates only the most harmful free radicals, thereby reducing oxidative stress and allowing the body to maintain optimal functionality and achieve balance.

At Vital Reaction, our H2 supplement is a natural antioxidant and anti-inflammatory molecule, which works rapidly to promote wellness and balance within the body, without adversely affecting cell signaling.

Moleculary Hydrogen, a unique antioxidant

Molecular hydrogen (H₂) is a unique antioxidant with the potential to revolutionize the self-care industry. By boosting your intake of this ordinary element (made extraordinary through our availability technology), you can reap multiple benefits. In the body, H₂ molecular hydrogen eliminates only the most harmful free radicals, thereby reducing oxidative stress and allowing the body to maintain optimal functionality and achieve balance.

Due to its extremely small size and superb bioavailability, a hydrogen supplement easily and rapidly travels far and wide throughout the body. It’s able to cross cell membranes, penetrating well into the cytoplasm of your cells and mopping up rogue free radicals. H₂ is a molecular hydrogen antioxidant that also crosses the blood brain-barrier with ease, and accesses parts of the cell that other antioxidants are incapable of reaching.

At Vital Reaction, our H₂ supplement is a natural antioxidant and anti-inflammatory molecule, which works rapidly to promote wellness and balance within the body, without adversely affecting cell signaling.

Free Radicals Cannot Be Eliminated — But They Can Be Limited

Free radicals are generated naturally — and inevitably — deep within our cells. They are a natural byproduct of the fundamental processes that enable us to generate energy from the foods we consume. There’s a reason we say we are “burning calories.” This energy-generating process literally uses oxygen to “burn” the molecules obtained from the food we ingest for fuel.

This process generates free radicals. In some instances, the immune system uses these highly reactive and potentially damaging molecules to attack foreign invaders and maintain robust immune function — so free radicals are not entirely negative.

As always, though, balance is everything. Many lifestyle activities — ranging from inactivity, to consuming fried foods, to avoiding fresh fruits and vegetables, to breathing polluted air — can affect one’s balance of antioxidants and free radicals.

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Molecular Hydrogen Tablets and Inhalation Machines From Vital Reaction

Consumable H₂ molecular hydrogen from Vital Reaction affords you the opportunity to boost your supply of one of nature’s most versatile, potent antioxidants. It’s the natural way to combat inflammation and promote healthful balance.

Vital Reaction offers high-quality molecular hydrogen products, including tablets and hydrogen inhalers. Tablets can be dissolved in drinking water for a quick boost, as part of your daily health regimen. With Vital Reaction, you get the most hydrogen per serving of any product on the market.

The most powerful antioxidant and anti-inflammatory, molecular hydrogen, offers these benefits:

  • Improve cognitive function
  • Reduce inflammation 
  • Promote cellular health
  • Increase energy
  • Have better skin health and tone
  • Improve sleeping patterns
  • Enhance athletic performance + decrease recovery time
  • Support healthy weight management
  • Hydrate at the cellular level
  • Prevent hangovers
  • Order Today

    Take charge of your health — and/or the health of your patients. Shop our molecular hydrogen supplements and inhalers today.

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